Prognostic gene expression profiling (GEP) tests for cutaneous melanoma (CM) are not recommended in current guidelines outside of a clinical trial.However, their use is becoming more prevalent and some practitioners are using GEP tests to guide patient management.Thus, there is an urgent need to bridge this gap Vitamins between test usage and clini
Mahmoud Ahmed Ali,1 Moustafa Adam El Taieb,1 Eisa Mohamed Hegazy,2 Hassan M Ibrahim,2 Alshimaa Abbas Mohamed,1 Mohamed Amer Ahmed Abdellatif,1 Nour Mohammed Ahmed,3 Ali Mohamed Younis1 1Dermatology, Venereology, and Andrology Department, Faculty of Medicine, Aswan University, Aswan, Egypt; 2Dermatology, Venereology, and Andrology Department, Facult
Abstract Background Protein-DNA interaction governs a large number of cellular processes, and it can be altered by a Belt Buckles small fraction of interface residues, i.e., the so-called hot spots, which account for most of the interface binding free energy.Accurate prediction of hot spots is critical to understand the principle of protein-DNA int